Abstract

Glioma is the most common primary malignant brain tumor in adults. It is resistant to traditional treatments or tends to invade brain functional areas. The current treatment options often lead to high rates of disability or mortality, emphasizing the urgent need for new therapies and approaches. Neurohomeostasis, which is responsible for maintaining normal physiological functions in body, plays a critical role in the development and progression of glioma. In the clinical management of glioma, it is important not only to target the tumor cells but also to address the neurohomeostatic imbalances before, during, and after surgery, for achieving better treatment outcomes. The exploration, development, and application of the neurohomeostasis theory in glioma treatment have the potential to develop current diagnostic and therapeutic strategies, offering new perspectives for the clinical management of this condition.

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