Abstract

At the end of 2019, a new disease—COVID-19—was identified, and a few months later, the World Health Organization announced a pandemic. It is now known that SARS-CoV-2 is highly contagious and most confirmed infections are mild to moderate. The situation is particularly difficult for dentists due to the high risk of virus transmission in the dental surgery. Complications including, but not limited to, problems with the respiratory and cardiovascular systems have been reported in patients with SARS-CoV-2. Several changes in the coagulation system, such as lower platelet numbers or increased prothrombin time, as well as increased D-dimer and fibrinogen, were observed. This review is intended to systematize the knowledge on the treatment of patients with congenital bleeding disorders (CBD) during the SARS-CoV-2 pandemic. Extensive literature research was conducted into COVID-19 and the general medical and dental treatment of patients with CBD. Case studies, research results and recommendations of international societies were used in the study. The results of this research are presented in the form of recommendations for the treatment of patients with coagulopathies. It should be remembered that the impact of COVID-19 on the health condition of patients with CBD is unknown to date.

Highlights

  • COVID-19 is an acute airway infection caused by severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) [1]

  • Based on measurements and recommendations from previous pandemics, many international public health, governmental and other societies have provided guidance which is regularly updated, and several approaches have been implemented in order to control transmission, including reliable monitoring of the SARS-CoV-2 transmission rates and severity, mitigation of the impact of COVID-19 in healthcare and social care settings, detection of clusters or outbreaks in specific settings, and, once achieved, maintenance of COVID-19’s elimination status

  • This review is limited to studies related to dental care, dentistry, oral medicine, precautions in dentistry during COVID-19/SARS-CoV-2 or Coronavirus pandemics in patients with congenital bleeding disorders (CBD), such as hemophilia, von Willebrand disease and other rare bleeding congenital disorders

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Summary

Introduction

COVID-19 is an acute airway infection caused by severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) [1]. Health Organization (WHO) declared the SARS-CoV-2 pandemic due to the public health threat [3]. The speed at which the virus spreads proves how contagious it is. This is not the first pandemic in human history, but it is the first to cover the whole world. Based on measurements and recommendations from previous pandemics, many international public health, governmental and other societies have provided guidance which is regularly updated, and several approaches have been implemented in order to control transmission, including reliable monitoring of the SARS-CoV-2 transmission rates and severity, mitigation of the impact of COVID-19 in healthcare and social care settings, detection of clusters or outbreaks in specific settings, and, once achieved, maintenance of COVID-19’s elimination status. The data on previous virus epidemic/pandemic procedures, such as

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