Practical monitoring of the clinical efficacy of sinquanon in patients on antibiotic therapy

Abstract

For more than seven decades, antibiotics and chemotherapeutics have been used successfully to treat and prevent infectious diseases, extensively changing the prognosis of severe infections and helping to improve quality of life. In the last two decades, the key role of the intestinal microbiota (IM) in basic vital functions such as digestion, protection against pathogens, and maintenance of immune and metabolic homeostasis has been recognized. Antibiotics do not selectively attack pathogenic bacteria. They have an effect on the normal microflora and can lead to imbalance inside the body (dysbacteriosis) and the development of opportunistic infections. Taking a probiotic during antibiotic treatment is one of the approaches to prevent antibiotic-associated diarrhea and other adverse effects of antibiotics when their use is necessary. In the present practical monitoring we want to share our results from the application of Sinquanon® to neutralize the negative effect of antibiotic treatment on the microbiome.