Abstract
If you want a gripping read I suggest you go out and buy The Beach by Alex Garland, but if you want to set up in situ hybridization, and particularly fluorescence in situ hybridization (FISH), in your laboratory, then this is the book for you. When you work in a department where FISH analysis is performed routinely, as I did, you can become blase about this powerful technique. Moving to a department where the technology is absent soon reminds one of how certain questions, such as 'which chromosome does this clone map to?' can be answered relatively quickly, and how publication quality data can be generated, using this approach. This book has convinced me to set up this technique again and although no money fell out when I opened it to start me on my way, it does provide a comprehensive list of the equipment and type of set-up required. The appendix contains a helpful list of suppliers, both of reagents and equipment.
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