Abstract
With the advent of safe lipid-lowering drugs, particularly statins and non-statin agents such as ezetimibe, and with the emergence of newer therapeutics such as monoclonal antibodies and RNA technologies, it has become apparent that major adverse cardiovascular (CV) events can be reduced both in primary and secondary prevention by 20–50% through lowering of low-density lipoprotein cholesterol (LDL-C) by 1–2 mmol/L. The purpose of this paper is to provide a pragmatic approach to the implementation of the 2021 Canadian Cardiovascular Society Guideline for managing dyslipidemia in adults.
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