Abstract

Rheumatoid arthritis (RA), an autoimmune disease of unknown etiology, is a serious threat to the health of middle-aged and elderly people. Although western medicine, traditional medicine such as traditional Chinese medicine, Tibetan medicine and other ethnic medicine have shown certain advantages in the diagnosis and treatment of RA, there are still some practical shortcomings, such as delayed diagnosis, improper treatment scheme and unclear drug mechanism. At present, the applications of artificial intelligence (AI)-based deep learning and cloud computing has aroused wide attention in the medical and health field, especially in screening potential active ingredients, targets and action pathways of single drugs or prescriptions in traditional medicine and optimizing disease diagnosis and treatment models. Integrated information and analysis of RA patients based on AI and medical big data will unquestionably benefit more RA patients worldwide. In this review, we mainly elaborated the application status and prospect of AI-assisted deep learning and cloud computation-oriented western medicine and traditional medicine on the diagnosis and treatment of RA in different stages. It can be predicted that with the help of AI, more pharmacological mechanisms of effective ethnic drugs against RA will be elucidated and more accurate solutions will be provided for the treatment and diagnosis of RA in the future.

Highlights

  • Rheumatoid arthritis (RA) is a non-fatal but currently incurable chronic symmetric autoimmune disease that involves multiple bones and joints, and their surrounding tissues, such as wrist joints, knuckles, metacarpophalangeal and metatarsophalangeal joints (Sparks, 2019; Scherer et al, 2020)

  • artificial intelligence (AI) has laid a scientific and technological foundation for the diagnosis and treatment system of RA in traditional medicine and western medicine, and the AI algorithm based on cloud data sharing is an indispensable part

  • Data acquisition and authenticity is our primary concern, these data mainly come from electronic medical record system of medical institutions, disease registration system, medical insurance system, public health survey and public health monitoring, birth/death registration database, genomics database, and other data generated in the process of disease prevention and health management (Wang et al, 2020; Zhu, 2020; Sun et al, 2021)

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Summary

Introduction

Rheumatoid arthritis (RA) is a non-fatal but currently incurable chronic symmetric autoimmune disease that involves multiple bones and joints, and their surrounding tissues, such as wrist joints, knuckles, metacarpophalangeal and metatarsophalangeal joints (Sparks, 2019; Scherer et al, 2020). AI integrated medical big data processing is to give a relatively fast mining of massive existing data such as the cause of intractable diseases, disease-specific clinical examination images, related available drugs, and disease development, outcome and prognosis through multiple open source data analysis platforms, which eventually and accurately diagnose disease and provide individualized reasonable treatment recommendations by comparing clinical signals of patients with simulated artificial algorithms (Torkamani et al, 2017; He et al, 2019; Dzobo et al, 2020).

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