Abstract

Meticulous attention to detail during the early postoperative period after lung transplantation is crucial for the overall success of the procedure. It starts in the intensive care unit with the initiation of immunosuppression, implementation of anti-infective strategies and stabilisation of respiratory function. The subsequent days and weeks on the regular ward focus on titration of immunosuppressive drugs, vigilant fluid management, early mobilisation and initiation of physiotherapy. In parallel, the lung transplant recipients are actively taught about self-monitoring and self-management strategies to allow for a smooth transition to outpatient follow-up care. This article intends to communicate the practical aspects and principles of the patient management used at the authors' centre on a daily basis by a multi-disciplinary transplant team, having at its core both a transplant pulmonologist and a thoracic surgeon. It focuses on the first month after lung transplantation, but does not cover surgical techniques, rare complications or long-term management issues of lung transplant recipients. The target audience of this practical guide are advanced trainees of pulmonology, thoracic surgery, intensive care, anaesthesiology and other clinicians involved in the early postoperative care of lung transplant recipients either in the intensive care unit or on the peripheral ward.

Highlights

  • Lung transplantation is an established therapeutic option for nonmalignant end-stage lung disease

  • Meticulous attention to detail during the early postoperative period after lung transplantation is crucial for the overall success of the procedure

  • It starts in the intensive care unit with the initiation of immunosuppression, implementation of anti-infective strategies and stabilisation of respiratory function

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Summary

Introduction

Lung transplantation is an established therapeutic option for nonmalignant end-stage lung disease. Many therapeutic strategies are based on expert opinion only or modified from experience with other solid organ transplant recipients, and some have stood the test of time after being adapted for LTRs. In the few available articles and book chapters covering the early postoperative management, the amount and level of detail of practical guidance varies considerably [1,2,3]. Many publications focus on an analytical approach, investigating, for example, aetiology, pathophysiology and therapeutic measures in the early postoperative phase. These articles generally do not mention the practical aspects of implementation with direct relevance to the attending physician. It is our aim to share our experience with colleagues new to the field and stimulate discussion and open up potential research areas

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