PP.25.15] THYROID ABNORMALITIES IN PRIMARY ALDOSTERONISM

Abstract

Objective: Primary aldosteronism (PA) is the most prevalent form of endocrine hypertension, so it is important to identify associated risk factors and pathologies. Several reports have shown increased prevalence of thyroid pathology in PA. Aim: To investigate morphological and functional alterations of thyroid gland in patients with PA. Design and method: Patients and methods: We investigated 93 cases of PA, among them 38 with aldosterone-producing adenoma /APA/ and 51 with idiopathic hyperplasia /IHA/. For ultrasonographic investigation we used Toshiba ECCOCEE equipment with linear transducer, frequency 10 MHz. Results: Among patients with PA thyroid pathology was found in 69 cases /74.19%/. In the whole group we identified 54 cases /57%/ with nodular goiter and 19 cases /20.43%/ with autoimmune thyroiditis. Among patients with APA thyroid pathology was found in 31 cases /81.56%/, among them 25 patients with nodular goiter /65.79%/ and 8 patients /22.39%/ with autoimmune thyroiditis. Among patients with IHA we found thyroid pathology in 34 cases /66.67%/, among them 26 patients /50.98%/ with nodular goiter and 10 patients /19.61%/ with autoimmune thyroiditis. Conclusions: The high prevalence of thyroid pathology in PA supports the recommendation that these patients have to be thoroughly investigated and adequately treated.