PP228-SUN GLUTAMINE AND INSULIN RESISTANCE FOR CARDIAC PATIENTS WITH DIABETES MELLITUS

Abstract

Rationale: The Edmonton Obesity Staging System (EOSS) [1] is a novel risk-classification system for obese patients in addition to BMI based on the presence or extent of comorbidities or functional limitations. The aim of this study was to apply EOSS to morbidly obese patients scheduled for bariatric surgery (BS). Methods: In 205 consecutive outpatients with indication for BS EOSS was assessed retrospectively using data from the patients’ medical files. Obesity-related metabolic, functional and psychological comorbidities were ranked on a 5-point ordinal scale, ranging from Stage 0 (no apparent obesityrelated risk factors/limitations) to Stage 4 (severe disabilities/limitations). Results: EOSS could be completed in 83.4% (171/205) of patients (59m, 112 f; median BMI 51.9 [35.1 89.9] kg/m2, median age 47 [19 67] yrs). The distribution of EOSS stages was 0% in Stage 0, 5.8% in Stage 1, 55.0% in Stage 2, 35.7% in Stage 3, and 3.5% in Stage 4. In 80.7% of patients metabolic disorders in combination with both functional and psychological problems were present. Significant and severe (Stage 3+4) metabolic disorders were more frequent (24.6%) than Stage 3+4 psychological (16.4%) or functional (10.5%) limitations. Conclusion: The EOSS is easily applicable and feasible in patients scheduled for bariatric surgery. Although these patients are highly selected we found a great variety in the type and severity of comorbidities and functional limitations. These results have to be accounted for when comparing studies in bariatric patients. The association of EOSS to outcome after BS warrants further investigation.