PP210-MON GASTROINTESTINAL COMPLICATIONS ASSOCIATED WITH THE USE OF SOY PROTEIN VERSUS CALCIUM CASEINATE IN ENTERAL NUTRITION IN TRAUMA PATIENTS

Abstract

Rationale: To determine the association between gastrointestinal complications and enteral nutritional support supplemented with soy protein versus calcium caseinate in traumatized critically ill patients admitted to intensive care at the Emergency Medical Center (UTICEM). Methods: Prospective randomized double-blinded clinical trial consisting of 40 patients admitted from June to October 2010. In the experimental group, patients received enteral nutrition by nasogastric or orogastric tube using polymeric formula with soybean protein (20% and 2.5 g) in 100ml of formula; in the control group patients received enteral nutrition using a polymeric formula with calcium caseinate (20% and 2.5 g) in 100ml of formula. Gastrointestinal complications studied were diarrhea, vomiting, bloating, and constipation. We included patients requiring enteral nutrition over 18 years whose families gave informed consent for participation in the study. Results: 95% of patients were male with a mean age of 33.5±13.6 years. The groups were comparable in terms of sex, age, protein intake, energy intake, and body mass index. No significant differences in gastrointestinal complications in the study group versus control group (25% of gastrointestinal complications in both groups) p = 1. In the study group 10% of patients had diarrhea and 15% vomiting; bloating was not observed in this group, whereas, in the control group 5% of patients hadbloating, 15% diarrhea an 20% vomiting. Conclusion: The use of isolated soy protein is not associated significantly with increased gastrointestinal complications in traumatized critically ill patients admitted to UTICEM.