PP028-MON PHASE ANGLE IS A PROGNOSTIC TOOL IN PEDIATRIC INTENSIVE CARE UNIT

Abstract

treatment for fever, inactivity of skeletal muscles, impaired microvascular blood flow). The aim of our study was to determine the influence of the severity of multiple organ failure in critically ill patients with septic shock on energy expenditure in these patients. Methods: Using indirect calorimetry, we assessed the energy expenditure in 50 patients (CEE) treated in the ICU for septic shock, mechanically ventilated and sedated, and we assessed the basal metabolic rate calculated from the Harissa-Benedict equation (BEE). The severity of multiple organ failure was specified using SOFA scale. Patients were also assessed by APACHE II score, taking into account the 28-day mortality. Energy expenditure was measured continuously over the first 24 hours of treatment by means of the Datex-Ohmeda M-COVX indirect calorimeter. Results: Mean EE value measured with a calorimeter (CEE) in septic shock patients was 1437±314 kcal/day or 20±4 kcal/kg BW/day. Their mean APACHE II score was 30.8, SOFA: 10.3. CEE in amounted to 62 137% of BEE (mean 102% of BEE). Statistical dependence between SOFA score and CEE was demonstrated. The measured value CEE patients decreases with increasing number of scale points SOFA. Statistical dependence between mortality and CEE was demonstrated. CEE in surviving patients (APACHE: 26.9, SOFA: 9.1) amounted to 91 137% of BEE (mean 113% of BEE). CEE in deceased patients (APACHE: 33.3, SOFA: 14) amounted to 64 124% of BEE (mean 92% of BEE). Conclusion: The severity of multiple organ dysfunction syndrome (MODS) in critically ill patients with septic shock is associated with decrease in total metabolic rate of these patients.