PP.01.34

Abstract

Objective: Microvascular angina includes a heterogeneous group of patients with typical chest pain, positive exercise stress test and angiographically smooth coronary arteries. Coronary heart disease is the most common type of heart disease and includes: stable angina pectoris, unstable angina pectoris, myocardial infarction without ST segment elevation (NSTEMI) and myocardial infarction with ST segment elevation (STEMI). The aim of this study was to examine differences in the values of mean arterial pressure in patients with microvascular angina and patients with CAD including: stable angina, unstable angina, STEMI and NSTEMI. Design and method: This study included 375 patients, of whom 75 with microvascular angina and 300 patients with CAD (75 patients with stable angina, 75 patients with unstable angina, 75 patients with NSTEMI and 75 patients with STEMI) who were treated at the Clinic for Cardiology, Clinical Centre Kragujevac in the period from 2005. to 2013. All patients with MVA were taken into account, while patients with CAD were randomised using randomising tables. Blood pressures were measured 30 minutes after admission. Mean arterial pressure was calculated as the sum of diastolic pressure and one-third of pulse pressure. All data was entered into SPSS and statistically processed using descriptive and analytical methods. Results: Values of mean arterial pressure were significantly different between patients with MVA and patients with CAD, with higher values in patients with CAD (98.07 ± 11.67 versus 103.27 ± 14.41; p = 0.001). When comparing values of mean arterial pressure between the groups (MVA vs. stable angina, unstable angina, NSTEMI and STEMI), significantly higher values were noticed between patients with MVA and NSTEMI (98.07 ± 11.67 versus 104.38 ± 14.11; p = 0.003) and patients with MVA and STEMI (98.07 ± 11.67 versus 109.04 ± 18.05; p < 0.001), while there was no significantly difference between patients with MVA and stable angina (98.07 ± 11.67 versus 100.27 ± 11.45; p = 0.246) and patients with MVA and unstable angina (98.07 ± 11.67 versus 99.40 ± 11.12; p = 0.475). Conclusions: Values of mean arterial pressure were significantly different between patients with MVA and CAD, more precisely between patients with MVA and patients with NSTEMI and STEMI, while the significance was not present between patients with MVA and stable and unstable angina pectoris.