PP.01.14

Abstract

Objective: The Cardiac syndrome X (CSX) includes patients, mainly women, fulfilling three main criteria: angina pectoris, a positive exercise-stress test and angiographically “clear” coronary arteries. The most manifest clinical symptom in those patients is chest pain. Aim of the current study is to assess characteristics of pain syndrome in patients with CSX compared with ischemic heart disease (IHD) pts. Design and method: We conducted a prospective randomized study including 56 consecutive patients (women) at the mean age 54,32 ± 9,52 who fulfilled criteria for CSX, hospitalized in the Clinic of Cardiology and 49 with IHD (mean age 63.2 ± 10.1years). For assessment of pain syndrome in CSX we used pain index, by which could be evaluated the subjective feeling of pain in these patients. Results: The results reveal strong statistical trend for subjective more strength feeling for pain in patients with CSX than in control group with IHD. In investigated group of patients with CSX is established significantly longer duration of episodes of stenocardial pain (mean 28,73 min), compared with IHD pts (mean 12.75 min), well as significantly higher mean duration and duplicate maximal duration than in patients with IHD. In pts with CSX first manifestation of typical stenocardial symptoms is mean 79,68 months after onset of menopause compared with IHD- 121,44 months. It is found that in patients with CSX the life-threatening fear feeling during the stenocardial attack is found in significant lower number of patients then in patients with IHD, respectively 25% and 80%. Conclusions: In patients with CSX is established increased pain perception, evaluated by pain index The duration in stenocardial attacks in patients with CSX is significant longer than in patients with IHD; There is a strong statistical trend for earlier manifestation of typical stenocardial symptoms from the onset of menopause in patients with CSX than in these with IHD; The manifestation of feeling of life-threatening fear during the stenocardial attack is just in a quarter in patients with CSX.