PP.37.02

Abstract

Objective: Investigate the sleep architecture in patients with Essential Hypertension and the relationship between Carotid-femoral pulse wave velocity (cfPWV). Design and method: Eighty six consecutive primary hypertension patients were included in the study, and 20 healthy volunteers served as controls. Conducted physical examinations, serological tests,24 hours ambulatory blood pressure monitoring, Carotid-femoral pulse wave velocity and polysomnography including sleep latency, total sleep time, Sleep efficiency, arousal index, nonrapid eye movement(NREM),rapid eye movement(REM) and the apnea–hypopnea index(AHI)for subjects. Results: In hypertension subjects, the sleep latency were (15.60 ± 15.04) minutes; the total sleep time were (409.82 ± 80.08)minutes; the sleep efficiency were (79.74 ± 13.07)%;the overall arousal index were (13.69 ± 10.84)p/h; the percentage of NREM1and 2 were(75.57 ± 11.01)% in the total sleep time, NREM 3 were (8.58 ± 6.63)% and the REM were (16.49 ± 10.78)%;at last the apnea–hypopnea index were(3.42 ± 1.31)p/h,all of these sleep parameters were different from the controls(p Conclusions: Our results suggest that the sleep architecture was abnomal in essential hypertension. The cfPWV was correlated with NREM3 and the arousal index of sleep characteristics in hypertension.