Abstract
From a total of 94 children (52-GA; 42-GB), 26/52(50%) and 30/42 (71%) infants of group A and B, respectively, had indication for PVZ prophylaxis. In GB, 14/30(47%) were immunized. The estimated cost of prophylaxis (5 doses) was 26,000€-GA and 30,000€-GB. Ten infants (17.8%) were admitted with RSV bronchiolitis: 8(31%)-GA and 2(6.6%)-GB, median age 4 months (range 1–22) and 80% male. In GA, 4(50%) children were admitted to paediatric intensive care unit (PICU), 3 needing mechanical ventilation. One infant was readmitted. In GB, one infant, admitted for 11 days in the PICU without mechanical ventilation, was infected 13 days after 2 doses of PVZ. The other, was admitted in the nursery 40 days after the fifth dose of PVZ. The total cost of admission was 36,129€-GA and 27,318€-GB. Comparing both groups, mechanical ventilation was only needed for GA (1.62 vs. 0; p=0.003). No differences occurred between total and PICU length of stay (8.8 vs. 10.5; p=0.07) (3.5 vs. 5.5; p=0.12).
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