PP-157 A New Diagnostic Maneuver for Cardioinhibitory Syncope

Abstract

Vasovagal syncope is the most common cause of syncope. Upright tilt table test is commonly performed for the evaluation of syncope, although the test has limited specificity, sensitivity, and reproducibility. The most frequent mechanism for vasovagal syncope is a cardioinhibitory response. Alterations in autonomic activation are responsible for cardioinhibitory syncope. Objective of our preliminary study is to investigate the potential diagnostic role of a maneuver previously described by Un et al. in patients with syncope. We hypothesize that maneuver significantly lowers heart rate in cardioinhibitory syncope patients with altering autonomic activation. Mentioned maneuver is consisted of quickly lying the subject backward from a seated to supine position (Figure1a). We enrolled 20 patients (10 syncope patients,10 healthy control) to this preliminary study. Study groups were constructed with sex and age matched participants. Median age was 25 years old in both groups.