PP.06.13] THE CLINICAL CHARACTERISTICS AND TREATMENT EFFICACY IN PATIENTS WITH HYPERTENSION ACCORDING TO THE RUSSIAN FEDERAL REGISTER OF ARTERIAL HYPERTENSION

Abstract

Objective: Hypertension remains one of the major risk factors leading to disability population. It is important to have information on how to treating patients with hypertension in the primary health care. Such information can be given by Registers. Design and method: Conducted a retrospective analysis medical data of 17,144 patients with hypertension from 18 regions of the Russian Federation included in the period 1.01.2012–31.12.2015. Results: The study included 6866 men and 10278 women aged 19–98 years. We divided patients into 2 groups based on years of inclusion in the Register. The 1st group consisted of patients enrolled in 2012–13, the 2nd - in 2014–15. The mean age was 62,5 ± 11,5 years. The control of quality evaluation of patients with hypertension was conducted by analyzing the amount of missing data on outpatient histories. At the required periods of outpatients were absent in a significant percentage of cases the following information: smoking (19,6% & 23,2%), family history (40,4% & 47,4%), waist circumference (80,2% & 67,8%), duplex scanning of brachiocephalic arteries (99,3% & 98,8%), echocardiography (80,3% & 63,9%), total cholesterol (14,7% & 13%), low-density lipoprotein (83,9% & 73,7%), triglycerides (66,4% & 58,4%), potassium (84,8% & 77,6%), glucose (13,3% & 14,8%), creatinine (55,9% & 38,9%), uric acid (97,5% & 96,1%). Classic risk factors (was calculated on the basis of all available data) have been identified in a large percentage of cases in both groups: in almost half of cases (46,6% & 44,8%) patients had a family history of early development of hypertension, physical inactivity was observed in 46,3%, still smoking at the time of inclusion in the Register was 36,6%, obese – 13%. At inclusion overage systolic BP was 156,8 ± 34,5 mmHg., diastolic BP – 83,1 ± 20,6 mmHg. In most cases, ACE inhibitors/angiotensin receptor blockers (ARB) (75,3%), beta-blockers (43,6%) and thiazide diuretics (37,3%) were recommended. The most frequently prescribed combinations were: ACE inhibitor/ARB + beta-blocker, ACE inhibitor/ARB + diuretic, ACE inhibitor/ARB + calcium antagonist. It is worth noting that in both groups combined treatment (78,3% & 81,2%) over monotherapy (21,7% & 18,8%) prevailed. The target BP was achieved approximately in 35,5%. Conclusions: We observed positive trend in the treatment of hypertension but the target BP is not achieved in all patients. Also necessary to broaden the ongoing prevention efforts aimed at lifestyle modification and risk factors.