Abstract
Objective: For use of indicators of Central aortic pressure (CAP) for the purpose of early diagnosis of preclinical atherosclerosis it is necessary to consider sexual features of the specified parameters. We investigated distinctions of indicators of the Central aortic haemodynamic between young men and girls. Design and method: Overall, 52 students from 19 to 23 years of age (25 boys and 27 girls) were recruited in this study according results of preventive medical exemanation. Investigation includes the BPLab®Vasotens Office device (Petr Telegin, Russia), which has passed quality ESH-2011 test. Waveforms were analyzed using the special automatic Vasotens® algorithm, which allows the calculation of central systolic (SYSao), diastolic (DIAao), mean (MBPao) and puls (PPao) blood pressure, central augmentation index (AIxao), amplification of the pulse pressure (PPA) and ejection duration (ED). We used BPStat software, version 05.00.04 (BPLab) to tabulate all the indices of every office measured wave form automatically. The data are presented as the median (25–75 percentile). An alpha level of 5% was considered to be statistically significant. The study was approved by the local ethics committee. Results: More significant differences (p less 0,05) between boys and girls were detected from AIxao -4 (-10-(-4)% opposite 5 (0–12) %. Levels of amplification of the central systolic and central pulse pressure were more higher in boys - 16 (13–19) opposite 10 (8–14) mm Hg and 18 (13–20) opposite 12 (10–15) mm Hg in girls. There were less significant differences between boys and girls from following signs: SYSao 109 (101–112) and 105 (100–103), DIAao 71 (66–79) and 73 (70–80), MBPao 86 (84–94) and 88 (82–93), PPao 35 (32–44) and 32 (28–37). Conclusions: Boys are characterized by presence of higher SYSao, PPao and level of amplification. In girls there were more higher indicators of DIAao, MBPao and ED. The obtained data aim on the need of the differentiated assessment of indicators of CAP at youth taking into account gender. Such approach will promote more effective formation of groups of risk among youth.
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