PP.01.30] PSYCHOLOGICAL STATUS SCORES RELATED WITH LEFT VENTRICULAR MASS INDEX AND MEAN AMBULATORY BLOOD PRESSURE VARIABLES IN PATIENTS WITH ARTERIAL HYPERTENSION

Abstract

Objective: Objective: The aim of our study was to determine correlations between psychological status and quality of life scores with left ventricular mass index and mean ambulatory blood pressure variables in patients with arterial hypertension (AH). Design and method: We analyzed 76 ambulatory blood pressure monitoring (ABPM) data of AH patients. ABPM monitor (Spacelabs 90207) was applied after the washout period. After ABPM session patients completed the QL questionnaire “General Well-Being Questionnaire” (J.Siegrist et al.). Left ventricular mass index (LVMI) (L. Teichholtz et all., 1976) was measured using echocardiography (Acuson 128XP). We assessed the following QL scale scores: I - physical well-being, II - physical performance, III - positive psychological well-being, IV - negative psychological well-being, V - psychological performance, VI - social well-being, VII - social performance. Also, patients completed the psychological questionnaire “Minnesota Multiphasis Personality Inventory” (MMPI). We analyzed the following MMPI scales: L – lie scale, F – aggravation scale, K – correction scale, 1 (Hs) – hypochondria, 2 (D) – depression, 3 (Hy) – hysteria, 4 (Pd) – psychopathy, 6 (Pa) – rigidity of affect, 7 (Pt) – psychasthenia, 8 (Sc) – schrizothemia, 9 (Ma) – hypomania. We used Spearman Partial Coefficient for correlation analysis adjusted for age, sex and duration of AH. Results: The mean ambulatory systolic BP (SBP) was 136.1 ± 11.2; diastolic (DBP) - 89.1 ± 9.0 mmHg (M ± SD). LVMI – 122,1 ± 24,9 g/m2. We found the following correlations: 1) 9 MMPI scale scores (energy, optimism, good mood) were negatively correlated with LVMI (r = -0.33, p < 0.05); 2) 9 MMPI scale scores had the negative relationships with clinical and ambulatory SBP levels (r = -0.23, r = -0.24 respectively, p < 0.05) and with SBP load variables (r = -0.25, p < 0.05). There were no significant links between QL scales scores and LVMI, ambulatory BP indices. Thus, energy, optimism, good mood (9 MMPI scale scores) had a negative correlation with LVMI, also to SBP indices. Conclusions: It was identified inverse correlation between energy, optimism, good mood and LVMI indices, and also with clinical and ambulatory SBP variables of AH patients. There were no links between QL scores and LVMI, ambulatory BP indices.