Povećana učestalost urinarnih infekcija izazvanih rodom Enterococcus kod pacijenata COVID-19 bolnice Kliničkog centra Vojvodine

Abstract

Objective. To investigate the frequency of isolates of various uropathogens in patients of the COVID-19 Hospital "Mišeluk" in comparison with patients from the nonCOVID-19 zone of the Clinical Center of Vojvodina (KCV). Methods. For the purpose of this study, information was collected on urine isolates sent from the COVID-19 hospital and the non-COVID-19 zones of the Clinical Center of Vojvodina in a three-month period, with samples from the non-COVID-19 zone KCV used as controls. Results. Of the 449 patients from the COVID-19 Hospital, the most common causative agents of intrahospital urinary infection (IUI) were members of the genus Enterococcus, (216/449; 48.10%), which in most cases caused IUI in women (127/216; 58.79%). The second most common causative agent of IUT in COVID-19 was Klebsiella pneumoniae (85/449; 18.93%). Of the 913 patients from the non-COVID-19 KCV clinics, the most common cause of IUI was Escherichia coli (249/913; 27.27%), predominantly in women (199/249; 79.91%, (ch2 (1) = 49,042). p <0.00001)). The second most frequent causative agents of IUTs were members of the genus Enterococcus, (216/913; 23.65%), with no significant difference in distribution between the sexes (ch2 (1) = 0.0833; p = 0.847). Conclusion. The most common causes of IUI in the COVID-19 KCV hospital were members of the genera Enterococcus and Klebsiella pneumoniae with almost equal distribution between the sexes. There was a statistically significant difference in the frequency of different IUI agents in the COVID-19 hospital patients versus the nonCOVID-19 KCV clinics. These results may be important in determining empirical therapy in patients of the COVID-19 KCV Hospital, as well as in planning procedures for the reduction of nosocomial infections.