Abstract
A non-invasive on-line monitoring system for blood electrolytes has been developed on the basis of potentiometric ion-selective silicon sensors. The microsensors were fabricated in the patented containment technology owned by ICB. Additionally, multianalyte sensors with two and three containment sensor elements integrated on chip were realized. The new polysiloxane membrane functionalized with trifluoropropyl groups with improved adhesion on the silicon oxide surface were used as matrix membrane for all prepared solid state microsensors. The following containment sensors have been developed: potassium, calcium, sodium, and pH. They were characterized in physiological test solutions. The excellent reliability of the potassium sensors has been demonstrated successfully in clinical trials with real circulating whole blood samples and on extracorporal animal blood circulation. First simultaneous measurements of potassium, sodium and pH have also been performed in vitro using human blood samples.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
