Abstract
We have assessed the influence of an attack of acute pancreatitis on the incidence of experimentally induced pancreatic cancer in rats. A low-protein diet plus repeated injections of DL-ethionine produced acute pancreatitis in rats. The animals were then fed either a diet of raw soya flour or a non-soya-containing diet and given repeated injections of azaserine, a weak pancreatic carcinogen. The rats that had recovered from acute pancreatitis developed pancreatic cancer, whereas those without previous pancreatitis did not. We conclude that the interaction of recovery from acute pancreatitis with a pancreatic carcinogen predisposes to pancreatic cancer in rats.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
