Abstract
Melastoma malabathricum Linn. is a shrub that belongs to the family Melastomataceae and a common herbal plant used in folk medicines to treat inflamed wounds. This study was carried out with the aim to evaluate the inhibitory activities of different concentrations of the M. malabathricum Linn. flower and fruit crude extracts against a variety of microorganisms. The inhibitory effects of both extracts were tested against the microorganisms using the disc diffusion method. The lowest concentrations of the extracts producing inhibition zones against the test microorganisms were used to determine their Minimum Inhibitory Concentrations (MICs) and Minimum Microbicidal Concentrations (MMCs). Both crude extracts showed strong inhibitory activities against Gram-positive bacteria. The range of MIC values for the crude flower and fruit extracts on all the bacteria tested were 12.5 to 100.0 mg/ml. Overall, Gram-positive bacteria were more susceptible to the crude extracts compared to Gram-negative species, potentiating a possible use of the extracts to inhibit or kill potential pathogens.
Highlights
In the present era, modern medicine develops very quickly and makes major contributions to worldwide diseases control
The results showed that S. sonnei ATCC 2593 was the most sensitive candidate towards the crude flower extract, with a minimal inhibition zone of 13.2 ± 0.2 mm
While P. mirabilis Institute of Medical Research (IMR) P184 and P. vulgaris IMR P147 exhibited the highest sensitivity towards the crude fruit extract with a 8.0 ± 0.0 mm inhibittion zone size
Summary
Modern medicine develops very quickly and makes major contributions to worldwide diseases control. Despite the rapid growth in knowledge and techniques in modern medicine, the populations of developed and developing countries show an increase interest in traditional medicines. According to the World Health Organization [1], the definition of traditional medicine may be summarized as the sum total of all the knowledge and practices, whether explicable or not, used in the diagnosis, prevention and elimination of physical, mental or social imbalances, and relying exclusively on practical experiences and observations handed down from generation to generation, whether verbally or in writing. Almost 80% of the Asian population relies on traditional medicine as a part of their health care regime. Is a shrub that belongs to the family Melastomataceae. It can be found abundantly in Malaysia.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
