Abstract
The desire to maintain youth as long as it possible in modern society, especially among women of working age, is primarily due to the desire to be in demand, well-groomed and attractive. Currently, there are 5 main methods that contribute to improving the condition of the skin of the face, namely: the method using professional cosmetics, chemical peels, mesotherapy, treatment with an injection of botulinum toxin type A (BTA) and intradermal implants based on hyaluronic acid.
 The aim of the literature review was to analyze the latest scientific data on the possibility of botulinum therapy in cosmetology.
 Wrinkles of open areas of the body (primarily on the face and in the decollete) have a negative effect on the emotional background and quality of life of women. In this regard, recently there has been a significant increase in demand for aesthetic medicine services, one of the areas of which is botulinum therapy (BT). Botulinum toxin type A (BTA) is a powerful neurotoxin that inhibits the release of acetylcholine in the neuromuscular junction. Injections of small doses of botulinum toxin type A into targeted mimic muscles cause their relaxation, which smoothes the underlying layer of the skin, thereby regressing mimic wrinkles. Today, according to officially approved indications, it is used in cosmetology, botulinum therapy is used to correct mimic wrinkles in the upper third of the face, drooping corners of the mouth, in the complex correction of the face oval, in the treatment of axillary and palmar hyperhidrosis. Blocking a tear mediator like acetylcholine, not only the presynaptic membranes of neuromuscular synapses are rich, but also many anatomical structures, such as glandular tissue (sweat, other glands, etc.). This commonality of the mechanism of action on various physiological processes in our body allows us to make an assumption about the great potential of botulinum therapy in the treatment of a number of diseases associated with impaired neuromuscular conduction.
Highlights
The desire to maintain youth as long as it possible in modern society, especially among women of working age, is primarily due to the desire to be in demand, well-groomed and attractive
There are 5 main methods that contribute to improving the condition of the skin of the face, namely: the method using professional cosmetics, chemical peels, mesotherapy, treatment with an injection of botulinum toxin type A (BTA) and intradermal implants based on hyaluronic acid
Recently there has been a significant increase in demand for aesthetic medicine services, one of the areas of which is botulinum therapy (BT)
Summary
В настоящее время существует большой арсенал средств и методов, способствующих улучшению состояния качества кожи лица: с использованием профессиональных косметических средств, аппаратных методик, лечение с помощью инъекции ботулинического токсина типа А (БТА), внутридермальных имплантов на основе гиалуроновой кислоты, аминокислотных и полипетидных составов и т. Ботулотоксин типа А (БТА) является мощным нейротоксином, который ингибирует высвобождение ацетилхолина в нервно-мышечном соединении. Согласно официально одобренным показаниям к применению в косметологии, ботулинотерапия применяется при коррекции мимических морщин верхней трети лица, опущенных уголков рта, в комплексной коррекции овала лица, в терапии аксилярного и ладонного гипергидроза.Универсальность применения БТА при коррекции мимических морщин и лечение локального гипергидроза обусловлены общим механизмом действия БТА: блокирование выброса такого медиатора, как ацетилхолин, которым богаты не только пресинаптические мембраны нервно-мышечных синапсов, но и многие другие анатомические структуры, например железистая ткань Ключевые слова: ботулотоксин типа А, ботулинотерапия, косметология, мимические морщины, эстетическая медицина. Вестник дерматологии и венерологии. 2020;96(5): Vestnik Dermatologii i Venerologii. 2020;96(5):
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