Abstract
Objective: To analyse Potential Years of Life Lost (PYLL) rates trends of lip, oral cavity and pharynx neoplasms in the Slovak population by age and gender. Material and Methods: The study analyses PYLL rates (age-standardized) of lip, oral cavity and pharynx neoplasms (C00-C14) per 100,000 in the period of six years (2010-2015). The study sample was divided into two age sub-categories (all ages: 0-69y. and working group: 20-69y.) National mortality data (C00-C14) (3,138 mortality causes) were analysed from the Statistical Office of the Slovak Republic. Results: The highest PYLL rate was found in sub-category 20-69 years in males (378 per 100,000) in 2012 and in females (64 per 100,000) in 2013. The highest PYLL rate was observed in sub-category all age groups in males (296 per 100,000) in 2012 and in females (50 per 100,000) in 2013. The PYLL rates of lip, oral cavity and pharynx neoplasms had in the period 2011-2015 upward trend in both sexes, however, in the 2014 was found the opposite trend. In 2015 the highest PYLL rates (non-standardized) in both sexes was found in age sub-category 55-59y. Conclusion: Our study should contribute to the development of oral cancer intervention programs.
Highlights
Lip, oral cavity and pharynx neoplasms (ICD-10 codes C00-C14) are an important public health problem [1] with an annual worldwide incidence estimated at approximately 529,500 cases (3.8% of all cancer cases) and mortality at 292,300 deaths (3.6% of cancer deaths) [2].In developing countries, risk factors for lip, oral cavity and pharynx neoplasms include the chewing tobacco, smoke tobacco, the consumption of nitrosamine-rich foods, the consumption of salted fish, the presence of human papillomavirus (HPV) [3] and alcohol consumption [4,5,6,7]
The Potential Years of Life Lost (PYLL) rates of lip, oral cavity and pharynx neoplasms had in the period 20112015 upward trend in both sexes, in the 2014 was found the opposite trend
In 2015 the highest PYLL rates in both sexes was found in age subcategory 55-59y
Summary
Oral cavity and pharynx neoplasms (ICD-10 codes C00-C14) are an important public health problem [1] with an annual worldwide incidence estimated at approximately 529,500 cases (3.8% of all cancer cases) and mortality at 292,300 deaths (3.6% of cancer deaths) [2].In developing countries, risk factors for lip, oral cavity and pharynx neoplasms include the chewing tobacco, smoke tobacco, the consumption of nitrosamine-rich foods, the consumption of salted fish, the presence of human papillomavirus (HPV) [3] and alcohol consumption [4,5,6,7]. Oral cavity and pharynx neoplasms (ICD-10 codes C00-C14) are an important public health problem [1] with an annual worldwide incidence estimated at approximately 529,500 cases (3.8% of all cancer cases) and mortality at 292,300 deaths (3.6% of cancer deaths) [2]. 75-80% of lip, oral cavity and pharynx neoplasms are attributed to tobacco and alcohol consumption [8]. In the Slovak Republic, prevalence of tobacco smoking is approximately 20% and the alcohol consumption is 115 litters of all alcoholic beverages (beer, wine, spirits) per person/year [9,10]. As a premature mortality measure, potential years of life lost (PYLL) provides estimating the average years a person would have lived if population had not died prematurely. Potential years of life lost is one of the most used indicator for the well-being population monitoring [13,14]
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