Abstract
Globally, cancer has been identified as one of the leading causes of death in public health. Its etiology is based on consistent exposure to carcinogenic. Plant-derived anticancer compounds are known to be less toxic to the normal cells and are classified into acetylenic compounds, phenolics, terpenes, and phytosterols. Dicoma anomala is a perennial herb belonging to the family Asteraceae and is widely distributed in Sub-Saharan Africa and used in the treatment of cancer, malaria, fever, diabetes, ulcers, cold, and cough. This review aimed at highlighting the benefits of D. anomala in various therapeutic applications with special reference to the treatment of cancers and the mechanisms through which the plant-derived agents induce cell death.
Highlights
Cancer has been identified as a major public health problem globally
Only one species (D. schinzii) out of the four exhibited similarities in terms of bioactive compound composition. These compounds are classified into different groups: acetylenic compounds, phenolic acids, flavonoids, sesquiterpenes, species, D. schinzii, D. capensis, D. anomala, and D. zeyheri have been investigated for medicinal use Dicoma and were Anticancer classified based on theirofphytochemical composition
Leaves of Dicoma anomala are extensivelyderived used infrom the treatment of various diseases triterpenes, These natural compounds plants seen to be non-toxic tosesquiterpenes, be The non-toxic to triterpenes, non-cancerous cells or normal cells, and these compounds areare used in the treatment and phytosterols. These natural compounds derived from plants are seen roots and leaves of Dicoma anomala are extensively used in the treatment of various diseases intoAfrica
Summary
Cancer has been identified as a major public health problem globally. In the United states, cancer is one of the leading causes of mortality [1]. The incidence and mortality rate of cancer in low- and middle-income countries are significantly increasing, and Zambia is of no exception [4]. The risk factors associated with cancers are divided into two categories based on their biological nature and modifiability. These are intrinsic and non-intrinsic risk factors. There are different approaches that are being used in the treatment and management of cancer such as chemotherapy, radiotherapy, surgery, gene therapy, and immunotherapy [8,9]. These modern therapies have shown some effectiveness in the treatment of cancer, they have adverse side effects [8]. These plants derived agents may be administered alone or simultaneously with other therapies such as chemo or radiotherapy [11]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
