Abstract
SummarySchiff base of acetylpyrazolone phenylhydrazone Ampp‐Ph was synthesized from the reaction of synthesized acetylpyrazolone diketone precursor Ampp with phenylhydrazine. On reacting the isolated Schiff base in ethanol with aqueous solution of manganese or nickel chloride salts afforded the metal complexes of acetylpyrazolone phenylhydrazone. Based on elemental, analytical and spectroscopic studies a bidentate keto tautomer Schiff base forming an octahedral complex with the metal ion has been proposed. Varying antibacterial activities against selected bacterial isolates have been observed using the paper disc diffusion method at 40mg/ml. A significant free radical scavenging (antioxidant) capability against DPPH was exhibited by the synthesized compounds.
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