Potential Role of Growth Hormone in a Pediatric Transient Ischemic Attack

Abstract

AbstractGrowth hormone (GH) is often prescribed in pediatric populations with short stature and is associated with several potential adverse events. One underrecognized potential adverse event is its effect on intracerebral vasculature, with concern for its ability to cause cerebrovascular accident. We present a pediatric case of presumed transient ischemic attack in the setting of chronic GH administration for idiopathic short stature syndrome. We propose potential pathogenic mechanisms for intracerebral vessel stenosis. We hope this case becomes a resource for clinicians and other healthcare providers when deciding whether or not to start GH in their young patients.