Potential of The Red Dragon Fruit (Hylocereus polyrhizus) as an Antioxidant in Strenuous Exercise

Abstract

Background and Objective: The increase of oxidative stress has negatively impacted several constituent components of cell membrane which include lipid peroxidation to form malondialdehyde (MDA), also related to liver function in which will release alkaline phosphatase enzymes. The purpose to know the protective of red dragon fruit (RDF) extract in strenuous exercise indicate the increase of MDA and alkaline phosphatase. Materials and Methods: The subject are 24 white male rats aged 3 months, weight of 200 g. They are grouped into 3 behavioral groups of 8 each. The strenuous exercise without red dragon fruit extract (SE-RDF) group: given treatment of strenuous exercise without the extract from RDF, the strenuous exercise with red dragon fruit extract 100 mg kg–1 b.wt., (SE+RDF 100) group: a treated with strenuous exercise and being given 100 mg kg–1 b.wt., of RDF extract and the strenuous exercise with red dragon fruit extract 200 mg kg–1 b.wt., (SE+RDF 200) group: given a dosage of 200 mg kg–1 b.wt. Results: The group SE+RDF 200 has the lowest malondialdehyde is 0.48 nmol mL–1 and alkaline phosphatase is 116.38 U L–1.The highest malondialdehyde is 0.78 nmol mL–1 and the highest alkaline phosphatase is 191.13 U L–1 is found at the group SE-RDF. Conclusion: The groups with strenuous exercise and being given 200 mg kg–1 b.wt., are better in responding to oxidative stress by having lower malondialdehyde and alkaline phosphatase compared to the other group.