Abstract
Type 2 diabetes mellitus (T2DM) is marked by early hyperglycemic symptoms and concurrent insulin resistance, leading to insulin secretion dysregulation. This resistance correlates with heightened Reactive Oxygen Species (ROS) level and reduced malondialdehyde. T2DM elevates malondialdehyde, necessitating antioxidant-rich interventions. Sunflower seed biscuits serve as a rich source of enzymatic antioxidants. The primary objective of this investigation was to substantiate the capacity of sunflower seed biscuits to ameliorate blood glucose and malondialdehyde level in T2DM-afflicted rats. Sunflower seed biscuits were investigated for their impact on blood glucose and malondialdehyde in 24 male Wistar rats. Rats were divided into four groups: diabetes rats (K-), simvastatin-treated (K+), receiving 0.72 g sunflower seed biscuits per rat body weight (X1), and 1.44 g (X2). Administered for 28 days via oral gavage, T2DM was induced through a high-fat diet and streptozotocin. Results showed significant blood glucose reduction in treatment groups (X1: 3.99 ng/mL, X2: 2.89 ng/mL) vs. controls (9.8 ng/mL), with statistical significance (p<0.05). Sunflower seed biscuits effectively lowered blood glucose and malondialdehyde in T2DM rats. The X2 group exhibited superior efficacy in reducing both parameters. Thus, sunflower seed biscuits present promise as a viable dietary option for T2DM management.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
