Abstract
BackgroundPeel is one of the major by-products in fruit processing industry. Fruit products (non-edible parts) are also considered as waste products and often discarded in the environment. Fruit peels are now serving as one of the primary sources for isolation and extraction of secondary metabolites in pharmaceutical industry. The present investigation was carried out to screen the phytochemical constituents and HPTLC analysis of peel extracts of Punica granatum and Citrus aurantifolia and their antidiabetic potential in alloxan-induced diabetic rats.ResultsAmong the different solvent extracts, methanol solvent extract was found to possess more amounts of secondary metabolites. In addition, HPTLC analysis of the plant samples revealed the presence of 13 peaks in both the plants by using gallic acid as marker. Different biochemical parameters such as blood glucose, cholesterol, protein, urea, creatinine, and triglycerides level were subjected for estimation by collecting the blood samples from the treated diabetic rats after 21 days. A sharp decline in blood glucose, cholesterol, triglycerides, creatinine, and urea level was noticed when methanolic extracts of Punica granatum and Citrus aurantifolia were given to experimental animals when compared with negative control. However, protein and weight of the animal were found to be enhanced when treated with methanolic extracts of both the plants.ConclusionIt can be concluded that fruit peels of both the plants exhibited antidiabetic potential on alloxan-induced diabetic rats which can be attributed to wide range of active pool of secondary metabolites. Further, screening and isolation of secondary metabolites along with their mode of action is required for effective use of plant-based drugs as antihyperglycemic agent.Graphical abstract
Highlights
Peel is one of the major by-products in fruit processing industry
The present study was made to evaluate the antidiabetic potential of fruit peel of Punica granatum and Citrus aurantifolia on alloxaninduced diabetic rats and identify the bioactive compounds using High Performance Thin Layer Chromatography (HPTLC) analysis
3.2 Phytochemical screening Differential occurrence of phytocompounds was observed when different solvent extracts of Punica granatum and Citrus aurantifolia were subjected to phytochemical screening
Summary
Peel is one of the major by-products in fruit processing industry. Fruit peels are serving as one of the primary sources for isolation and extraction of secondary metabolites in pharmaceutical industry. The present investigation was carried out to screen the phytochemical constituents and HPTLC analysis of peel extracts of Punica granatum and Citrus aurantifolia and their antidiabetic potential in alloxan-induced diabetic rats. Fruit and vegetable wastes are used to extract and isolate potential bioactive compounds and used in the food, pharmaceutical, cosmetics, and textile industries. Studies have revealed that appreciable quantity of phytochemical compounds and other essential nutrients are present in the seeds, peels, and other components of fruits and vegetables [5]. The present study was made to evaluate the antidiabetic potential of fruit peel of Punica granatum and Citrus aurantifolia on alloxaninduced diabetic rats and identify the bioactive compounds using HPTLC analysis
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Beni-Suef University Journal of Basic and Applied Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
