Abstract
Bone grafts play a pivotal role in bone regenerative surgeries. Each physician from orthopedics to dentistry knows the three fundamental mechanisms of bone grafting that are osteo conduction, osteo-induction, and osteogenesis. However, there is a huge lacuna in the basic understanding of the variation and range of the function of the graft materials falling under the basic three categories. The popular tissue engineering “biological triad” consisting of cells, scaff old, and growth factors, remains the main stay of bone grafting techniues. However, the clinical success of bone grafting remains upheld by the basic understanding of their significant factors apart from the 3basic factors mentioned in tissue engineering triangle. An attempt has been made in the current article to acknowledge the rest of the important factors driving the clinical success of graft surgeries. The article further addresses all the recent modifications made to the tissue engineering triangle by providing special emphasis on Calcium phosphate osteo inductive graft materials due to their uniue MP promoting properties. The application of bone ceramics or calcium phosphates has increased tremendously over the past decade.
Published Version
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