Abstract
Malaria is an infectious disease with a high morbidity and mortality rate caused by Plasmodium and is transmitted through the Anopheles mosquito. Garlic (Allium sativum) has active substances that can be used as medicinal ingredients. Several active substances, namely allicin, ajoene, and quercetin contained in garlic have the potential to act as an effective and safe anti plasmodium for the host. This writing is a literature review using relevant literature. The results of the study concluded that the active ingredients in garlic have potential to be a new antimalarial agent, and it is hoped that it can be a cheaper and more effective malaria treatment so that drug resistance and morbidity and mortality from malaria can be reduced.
Highlights
Malaria is an infectious disease caused bySince 2004, Artemisinin CombinationProtozoa belonging to Apicomplexa, namely Therapy has been started in the form of artemisininPlasmodium which is transmitted by Anopheles amodiaquine to replace chloroquine preparation mosquito
Malaria is causing high morbidity and efficacy so that it is replaced with another mortality worldwide
A definite diagnosis of malaria is ingredients that have been identified, ajoene, established through microscopic examination by allicin, and quercetin are believed to be some of the finding plasmodium in thick or thin peripheral active substances that are useful as antimalarials.[6,7,8] blood smear
Summary
Journal Homepage: https://jofh.org/ Volume 1 | Nomor 1 | Desember 2021 e-ISSN: 0000-0000. The Potential of Allicin, Ajoene and Quercetin Contained in Garlic (Allium sativum) as a Promising Anti-Malarial. 1 1Medical Student, Faculty of Medicine, Sam Ratulangi University, North Sulawesi, Indonesia 2 2Division of Clinical Parasitology, Faculty of Medicine, Sam Ratulangi University, North Sulawesi, Indonesia. Article History: Received: 31 August 2021 Received in Revised Form: 31 August 2021 Accepted: 31 August 2021 Available Online: 31 August 2021
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