Abstract
In addition to the benefits of pesticides frequently used in the agricultural sector, there are also many negative effects on the environment and living organisms. We aimed this study was to investigate mutagenic activity of Udimo 75 WG herbicide that commonly used in the agricultural sector by Ames/Salmonella microsome short-time test system. Experiments were applied in the absence (-S9) and presence (+S9) of enzymes in the metabolic activation by using TA98 and TA100 strains of Salmonella typhimurium. At first, the cytotoxic doses of the test substances were detected and then, 5 non-cytotoxic dose for each test substances were selected. For the mutagenicity of Udimo 75 WG 500, 250, 125, 62.5 and 31.25 μg/plate doses were studied. The obtained data were statistically analysed by Dunnett's t-test and the results were evaluated by compare with spontaneous control plates. According to the results of this study, Udimo 75 WG herbicide showed mutagenic activity both in the absence and presence of S9 fraction at the dose of 500 μg/plate concentration in both strains. Therefore, this herbicide may be in the genotoxic risk group for humans and other living things.
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