Abstract
Potential metal chelating ability of mycosporine-like amino acids: a computational research
Highlights
Mycosporine-like amino acids (MAAs) were originally found in 1960s [1] and have attracted attention ever since
There are many reviews written about their structures, biosynthesis [2,3,4]; roles such as antioxidant molecules, compatible solutes, nitrogen reservoirs; protection against UV-radiation, dessication or thermal stress, [5,6,7] as well as their biotechnological and industrial potential as natural sunscreens, antiphotoaging molecules, stimulators of skin renewal and functional ingredients of UV-protective biomaterials [8,9,10,11]
We modeled iron-MAA complexes for the MAAs shown in Fig. 1
Summary
Mycosporine-like amino acids (MAAs) were originally found in 1960s [1] and have attracted attention ever since. They refer to two studies that hypothesize MAAs could play a role due to chelation of iron and calcium for this unknown mechanism of inhibition [44].
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