Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome

Francesco Ciccia,Riccardo Alessandro,Annarita Giardina,Giuseppina Campisi,Aroldo Rizzo,Francesco Dieli,Giovanni Triolo,Angelo Ferrante,Stefania Raimondo,Giuliana Guggino

doi:10.1136/ard.2011.154013

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome

Francesco Ciccia, Riccardo Alessandro + Show 8 more

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https://doi.org/10.1136/ard.2011.154013

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Journal: Annals of the Rheumatic Diseases	Publication Date: Oct 6, 2011
Citations: 150	License type: other-oa

Affiliation: University of Palermo, Ospedale Vincenzo Cervello

#Natural Killer Cells #Quantitative Gene Expression Analysis + Show 8 more

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Abstract

ObjectivesIn chronic inflammatory disorders, interleukin (IL)-22 may act either as a protective or as a pro-inflammatory cytokine. At mucosal sites, IL-22 is mainly produced by CD4+ T cells and by...

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