Abstract

State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences; Department of Biochemistry and Molecular Biology, Peking Union Medical College, Tsinghua University; Beijing 100005, China; Department of Emergency Medicine, Peking Union Medical Collage Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China; Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China; Laboratory of Molecular Genetics of Aging & Tumor, Medical Faculty, Kunming University of Science and Technology, Chenggong Campus, Kunming 650500, China

Highlights

  • West African countries are currently suffering the most severe pandemic of Ebola virus disease ever recorded, with 4269 human cases and 2288 deaths, and the number of cases in the current outbreak exceeds the number from all previous outbreaks combined

  • The current outbreak in the West African countries is caused by the Zaire Ebola virus, and no specific treatment for the disease is yet available

  • Ebola virus has the special thread-like structure seen on electronic micrographs

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Summary

Introduction

West African countries are currently suffering the most severe pandemic of Ebola virus disease ever recorded, with 4269 human cases and 2288 deaths (through 6 September 2014), and the number of cases in the current outbreak exceeds the number from all previous outbreaks combined. The current outbreak in the West African countries is caused by the Zaire Ebola virus, and no specific treatment for the disease is yet available. It is reported that bats could be a possible reservoir, and they may support the replication of Ebola virus without symptoms of the disease. Ebola virus disease is believed to occur after an Ebola virus is transmitted to a human via contact with an infected animal.

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