Potential applications of the human amniotic membrane in endodontics: A case series of three different procedures

Abstract

The human amniotic membrane (hAM) is the innermost placental membrane that protects and nourishes the growing fetus. While its use in various oral and maxillofacial procedures is abundant, application in endodontics is relatively new. The present case series describes the application of this therapeutic membrane in three different endodontic procedures – pulpotomy, revascularization, and root-end surgery. In case 1 (pulpotomy), the radicular pulp returned to its uninflamed state, and the patient became asymptomatic at follow-up. In case 2 (revascularization), the patient became asymptomatic; however, there was no increase in the root length and width even after 2 years of follow-up. In case 3, the osseous bone defect was healed entirely at the 6-month follow-up. The application of hAM in different endodontic treatment protocols seems appreciable. A potential limitation of its use has been described in this report. Further clinical trials are warranted to produce better evidence for the same.