Abstract
Over the decades, the world has witnessed diverse virus associated pandemics. The significant inhibitory effects of marine sulfated polysaccharides against SARS-CoV-2 shows its therapeutic potential in future biomedical applications and drug development. Algal polysaccharides exhibited significant role in antimicrobial, antitumor, antioxidative, antiviral, anticoagulant, antihepatotoxic and immunomodulating activities. Owing to their health benefits, the sulfated polysaccharides from marine algae are a great deal of interest globally. Algal polysaccharides such as agar, alginate, carrageenans, porphyran, fucoidan, laminaran and ulvans are investigated for their nutraceutical potential at different stages of infection processes, structural diversity, complexity and mechanism of action. In this review, we focus on the recent antiviral studies of the marine algae-based polysaccharides and their potential towards antiviral medicines.
Highlights
Marine biotechnology is a rapidly developing arena which utilizes marine organisms to produce, modify or improve biological resources for industrial, food, medical or environmental applications
Algal polysaccharides exhibited significant role in antimicrobial, antitumor, antioxidative, antiviral, anticoagulant, antihepatotoxic and immunomodulating activities. Owing to their health benefits, the sulfated polysaccharides from marine algae are a great deal of interest globally. Algal polysaccharides such as agar, alginate, carrageenans, porphyran, fucoidan, laminaran and ulvans are investigated for their nutraceutical potential at different stages of infection processes, structural diversity, complexity and mechanism of action
We focus on the recent antiviral studies of the marine algae-based polysaccharides and their potential towards antiviral medicines
Summary
Marine biotechnology is a rapidly developing arena which utilizes marine organisms to produce, modify or improve biological resources for industrial, food, medical or environmental applications. Algae, being a large part of marine ecosystem, contributes an inevitable role in food and pharmaceutical industry. Marine algae are low in calories since the lipid content is low. They are rich in carbohydrate content and dietary fibers. Marine algae contain large amounts of polysaccharides, majorly as cell wall structural component and storage carbohydrates. The seaweed polysaccharide concentrations vary from 4–76% of the dry weight depend on the species [5]. Considering the storage polysaccharides, in green algae depending on the species, it has polysaccharides such as sulphated galactans, xylans, ulvans, cellulose and xyloglucan. Carrageenans, floridean starch, porphyran, and xylans [6,7,8]
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