Abstract
Background: Marine microorganisms such as algae were identified a rich sources of biologically active compounds. This study was designed to explore the in vitro antioxidant, anti-apoptotic and anti proliferative activities of different algae [Gracilaria dendroides (GD), Dictyota ciliolata (DC) and Cladophora socialis (CS)] extracts obtained from Red sea at Jeddah. Materials and Methods: Algae extracts (ethanol, chloroform and water) were tested for antioxidant activity for free radical scavenging and secondly as anti-apoptotic and anti-proliferative activity against different cell lines. Antioxidant capacity was detected by evaluation superoxide anion radicals, reducing potential and assay of phenolic and flavonoid content in extracts. Results: Chloroform extract of DC (CEDC) was found to have a better free radical scavenging activity (IC50= 310.58 g/ml) than methanol extract (MEDC). MEDC (IC50= 522 g/ml). The phenol level in CEDC and MEDC were 50.1 and 38.18 mg, while flavonoids were 65.58and 41.74 /mg.EDC and EDC were showed ant proliferative against MC7 and HALA 1. Conclusion: The solvents extracts exhibited promising biological activity as antioxidants and ant proliferative action.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
