POTENTIAL ANIMAL POISONS FOR DEVELOPMENT OF ANTIVIRAL THERAPEUTICS

Abstract

Recent serious effects of viral infections on humans, anti-viral compound research has gained momentum and has become very important. In particular, viruses such as Cytomegalovirus/CMV, Epstein Barr virus/EBV, Hepatitis B/HBV, Hepatitis C/HCV, Herpes Simplex Virus/HSV, Human Immunodeficiency Virus/HIV, rabies virus, corona virus and Ebola virus are of high importance. Very limited antiviral medicines commercially available and can cause serious-significant side effects for patients receiving treatment. Also, viruses have the mutational capability to infect host cells. For this reason, in recent years, the possibility of producing new antiviral medicines, especially from natural sources, has increased considerably, and animal-based products are now also promising among natural products. Viral-borne infections have been known long ago. However, it was just possible to isolate these viruses that cause infection in the nineteenth century. The management of viral infection, the isolation of the virus, and the control of viral reproduction has played a role in the development of many drugs and vaccines in the studies carried out since that period. In addition to these studies, viruses continue to be one of the primary causes of human and animal diseases today. It has been stated that Antiviral Peptides/AVPs can be used as a defense barrier with previous studies. Some AVPs are known to show a broad spectrum against viruses. In this direction, many studies have been conducted on AVPs and it has been observed that these peptides inhibit the viral particle by the above-mentioned mechanisms. In this study venoms and toxins of some animals, which have antiviral activities are overviewed. Peer Review History: Received 24 March 2021; Revised 15 April; Accepted 28 April, Available online 15 May 2021 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Asia Selman Abdullah, Al-Razi university, Department of Pharmacy, Yemen, asia_abdullah65@yahoo.com Dr. Nuray Arı, Ankara University, Turkiye, ari@ankara.edu.tr Dr. Terhemen Festus Swem, Department of Veterinary Physiology and Biochemistry, College of Veterinary Medicine, Federal University of Agriculture, Makurdi, Benue State, Nigeria, swemfestus422@gmail.com Similar Articles: EVALUATION OF ANTIBACTERIAL RESISTANCE OF BIOFILM FORMS OF AVIAN SALMONELLA GALLINARUM TO FLUOROQUINOLONES