Abstract

Proton pump inhibitors, the most potent and safest acid inhibitory agents available, irreversibly bind and inhibit H+, K+-ATPase. They inhibit all phases of gastric acid secretion. Proton pump inhibitors are considered extremely safe and are regularly prescribed. They may, however, have side effects. They affect the clearance of other medicines. And the reactions to them may mimic other conditions and side effects of other medicines.

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