Abstract
The synthesis and biological activities of several glycopeptidolipids derived from muramyl dipeptide (MDP) are described. In combination with gamma interferon (INFγ) MDP derivatives 3c and 3d carrying glycyrrhetinic acid as rigid β-aglycone synergise the action of the lymphokine in the release of H 2O 2 by activated human macrophages, while MDP derivatives 3a and 6a carrying the more flexible diphytanyl glycerol β-aglycone inhibit it.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
