Potency of Purple Yam (Dioscorea alata L) as an Immunomodulatory Agent

Sri Nabawiyati Nurul Makiyah,Muhammad Sasmito Djati

doi:10.20527/jbk.v14i1.4589

Abstract

Abstract: Purple yam tuber (Dioscorea alata L.) is one of tubers that has not been used optimally. One of the nutrients contained in Dioscorea species is Saponin Steroid. This paper aims to examine the potential of Steroid Saponin in purple yam tuber (Dioscorea alata L.) as an immunomodulatory agent. The method is by reviewing from various literatures. This article found that Steroid Saponin in purple yam tuber (Dioscorea alata L.) had a potency as an immunomodulatory agent. Keywords: Purple yam tuber (Dioscorea alata L), Steroid Saponin, Immunomodulatory

Highlights

Purple yam tuber (Dioscorea alata L.) is one of tubers that has not been used optimally.Some of the nutrients contained in Dioscorea species are carbohydrate, essential amino acid, mineral, polyphenol, mucin (Glycoproteins), purin derivatives and steroid saponins.[1,2,3,4,5,6,7,8,9,10] Dioscorea alata L. contained diosgenin[11] which is the major aglycone of steroid saponin acting as an intermediate steroid in the pharmaceutical industry
Steroid saponin is the most important bioactive compound due to its several biological functions, such as anticarcinogenic, antithrombotic, antiviral, hemolytic, hypocholesterolemia, hypoglycemic, immunostimulatory, antitumorigenic, anti-mutagenic, immunomodulatory and anti-inflammatory depending on its structure.[6,7,8,9]
This article aims to find the potency of steroid saponin in purple yam tuber (Dioscorea alata L.) as an immunomodulatory agent

Summary

INTRODUCTION

Purple yam tuber (Dioscorea alata L.) is one of tubers that has not been used optimally. Some of the nutrients contained in Dioscorea species are carbohydrate, essential amino acid, mineral, polyphenol, mucin (Glycoproteins), purin derivatives Alantoin) and steroid saponins.[1,2,3,4,5,6,7,8,9,10] Dioscorea alata L. contained diosgenin[11] which is the major aglycone of steroid saponin acting as an intermediate steroid in the pharmaceutical industry. This article aims to find the potency of steroid saponin in purple yam tuber (Dioscorea alata L.) as an immunomodulatory agent

DISCUSSION

EFFECTS OF SAPONINS ON THE IMMUNE SYSTEM

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