Potato Fibers Have Positive Effects on Subjective Appetite Sensations in Healthy Men, but Not on Fecal Fat Excretion: A Randomized Controlled Single-Blind Crossover Trial.

Tanja Kongerslev Thorning,Christian Ritz,Anne Raben,Mette S Nielsen,Arne Astrup,Christel Johanneson Bertolt

doi:10.3390/nu12113496

Abstract

Dietary fibers can affect appetite and gut metabolism, but the effect of the novel potato fibers FiberBind and rhamnogalacturonan I (RG-I) is unknown. We, therefore, aimed to investigate the effect of daily intake of FiberBind and RG-I on appetite sensations and fecal fat excretion. In a single-blinded, randomized, three-way crossover trial, wheat buns with FiberBind, RG-I, or low fiber (control) were consumed by 18 healthy men during a 21-day period. Appetite sensation and blood samples during a 3 h meal test, fecal fat content, and ad libitum energy intake were assessed after each period. Compared to RG-I and control, FiberBind caused a higher composite satiety score (6% ± 2% and 5% ± 2%), lower prospective food consumption (5% ± 2% and 6% ± 2%), and lower desire to eat (7% ± 3% and 6% ± 3%) (all p < 0.05). FiberBind also caused higher satiety (6% ± 2%) and fullness (9% ± 3%) compared to RG-I (all p < 0.01). No effects on fecal fat excretion or energy intake were found. The RG-I fiber caused higher postprandial glucose concentration compared to FiberBind (p < 0.05) and higher insulin concentration at 180 min compared to control (p < 0.05). Compared to the control, RG-I and FiberBind lowered peak insulin concentration (both p < 0.05) and delayed time to peak for glucose (both p < 0.05). In conclusion, FiberBind intake could be beneficial for appetite regulation, but neither FiberBind nor RG-I affected fecal fat excretion or energy intake.

Highlights

The incidence of obesity is increasing worldwide
FiberBind increased the postprandial feelings of satiety and reduced the feelings of hunger compared to rhamnogalacturonan I (RG-I) fiber and the control
FiberBind had a beneficial effect on appetite regulation, delayed the glucose peak, and lowered the insulin peak

Summary

Introduction

The incidence of obesity is increasing worldwide. This is a major health concern since obesity is a risk factor for the development of various diseases, including type 2 diabetes, cancer, and cardiovascular diseases [1]. Some dietary fibers can affect energy absorption by increasing fecal fat excretion [2], and viscous fibers in particular have been shown to suppress appetite sensations and reduce subsequent energy intake [3,4]. Dietary fibers may delay the gastric emptying rate, prolong the small intestine transit time, and thicken the unstirred water layer [6], thereby reducing the nutrient absorption rate [3,7,8], prolonging gut hormone release [9], and possibly increasing the satiety response

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Conclusion