Abstract

It was shown for the first time that pentaamino acid derivative of fullerene C60 (potassium salt of fullerenylpenta-N-dihydroxytyrosine) effects on three targets of type 2 diabetes mellitus. It competitively inhibits the enzymes aldose reductase and sorbitol dehydrogenase and also exhibits antiglycation effect on bovine serum albumin. The enzymes inhibition constants were calculated.

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