Abstract
The objective of this study was to investigate the associations between potassium and obesity/metabolic syndrome. We identified eight relevant studies and applied meta-analysis, and nonlinear dose-response analysis to obtain the available evidence. The results of the pooled analysis and systematic review indicated that high potassium intake could not reduce the risk of obesity (pooled OR = 0.78; 95% CI: 0.61â1.01), while serum potassium and urinary sodium-to-potassium ratio was associated with obesity. Potassium intake was associated with metabolic syndrome (pooled OR = 0.75; 95% CI: 0.50â0.97). Nonlinear analysis also demonstrated a protective effect of adequate potassium intake on obesity and metabolic syndrome. Adequate intake of fruits and vegetables, which were the major sources of potassium, was highly recommended. However, additional pertinent studies are needed to examine the underlying mechanism.
Highlights
Central obesity has become a worldwide problem within the last several decades, and the prevalence of obesity remains high
Inclusion criteria were applied as the following: the study must (1) describe the association between potassium and obesity/Metabolic syndrome (MetS); (2) be an original study published in English prior to October 2015; and (3) have key data for meta-analysis or dose-response analysis
MetS, and our study reviewed the effect of different measurement of potassium on obesity and MetS in detail
Summary
Central obesity has become a worldwide problem within the last several decades, and the prevalence of obesity remains high. More than 33% of adults and 17% of youths in the United States [1], and 26.3% of adults in Germany, where the prevalence is among the highest in Europe [2], are obese. Metabolic syndrome (MetS), which is known as a cluster of obesity-driven alterations, such as central obesity, insulin-resistance, dyslipidaemia, and hypertension [4], has received increasing attention in recent years as its prevalence and public health burden have increased worldwide [5]. Substantial evidence shows that MetS is associated with diabetes [6,7], dyslipidaemia, cardiovascular disease [7,8], specific types of cancer [3,9], and many other conditions.
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