Potassium (1‐Organo‐1H‐1,2,3‐triazol‐4‐yl)trifluoroborates from Ethynyltrifluoro­borate through a Regioselective One‐Pot Cu‐Catalyzed Azide–Alkyne Cycloaddition Reaction

Abstract

AbstractA novel series of 1,4‐disubstituted 1,2,3‐triazole‐containing potassium trifluoroborates were prepared in good to excellent yields from the corresponding organohalides and potassium ethynyltrifluoroborate through a regioselective one‐pot Cu‐catalyzed azide–alkyne cycloaddition (CuAAC) reaction. Further Suzuki–Miyaura cross‐coupling of these (organo‐1,2,3‐triazol‐4‐yl)trifluoroborates with aryl and alkenyl bromides by using a PdCl2(dppf)·CH2Cl2/TBAB [dppf = 1,1′‐bis(diphenylphosphanyl)ferrocene, TBAB = tetrabutylammonium bromide] system under microwave irradiation was explored.