Abstract
ABSTRACT This study aimed to explorethe relationship between post-vaccination adverse reactions, decision regret,and willingness to pay (WTP) for the booster dose. An online survey was conductedin Taizhou, China. Questionnaires were completed by 1,085 healthcare workers(HCWs) and 1,054 (97.1%) have received two doses of the COVID-19 vaccine.Mediation analysis method was adopted. Our study presented that post-vaccinationadverse reactions in HCWs could decrease their WTP for the booster dose. Ofnote, HCWs experienced adverse reactions after vaccination would more likely regrettheir previous vaccination decisions, which, in turn, further reduced their WTPfor a booster shot. Decision regret mediated the relationship between adversepost-vaccination reactions and WTP for the booster dose. The findings impliedinextricable relationships among post-vaccination adverse reactions, decisionregret, and WTP of the booster dose. It suggested that these post-vaccination adverse reactions should be furtherincorporated into vaccine campaigns to improve vaccine intention andpotentially increase willingness to pay for booster doses of COVID-19 vaccine.
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