Abstract
The parameters of posttetanic hyperpolarization (PTH) of a single node of Ranvier are unchanged by an increase of duration of stimulation of over 0.1 sec. PTH was not sensitive to strophanthin but was abolished by tetraethylammonium. The membrane resistance of the Ranvier node, measured by the amplitude of anodic shocks, was reduced by 50% during PTH. It is concluded that PTH of isolated nerve fibers is due to preservation of increased potassium permeability during and after the end of tetanus. An increase in the duration of tetanization does not cause the appearance of PTH connected with active ion transport.
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